WHOOPING COUGH VERSUS COQUELUCHOIDE SYNDROME

Pathology	WHOOPING COUGH	COQUELUCHIDE SYNDROME
DEFINITION	IT IS AN IMMUNE PREVENTABLE DISEASE OF AN INFECTIOUS TYPE THAT MAINLY AFFECTS THE HIGHEST AERIAL ROADS AND IS EXTREMELY INFECTIOUSA	IT IS A DISEASE THAT CAN BE OF INFECTIOUS TYPE, NOT INFECTIOUS OR BOTH THAT MAINLY AFFECTS THE SUPERIOR AIRWAY
ETIOLOGY	BORDETELLA PERTUSSIS BORDETELLA WITH OTHER VIRU AND BACTERIA	NFECTIOUS BORDETELLA PARAPERTUSSIS, BORDETELLA BRONCHISEPTICA, MICOPLASM PNEUMONIAE, CHLAMYDÓFILAS, RINOVIRUS, BOCAVIRUS, METANEUMOVIRUS, ADENOVIRUS, SINCTIAL RESPIRATORY VIRUS (VSR) VIRUS PARAINFLUENZA 1, 3, 4; INFLUENZA VIRUS, BRAMANHELLA CATARRALIS, CANDIDA ALBICANS. NOT INFECTIOUS THE GASTROESOFÁGICO REFLUX, BRONCHIAL ASTHMA, ASPIRATION OF STRANGE BODIES, ASPIRATION OF TOXIC SUBSTANCES, CYSTIC FIBROSIS, ADENOPATHIES, EXTERNAL OR INTERNAL COMPRESSIONS, BRONCHIAL HYPERREACTIVITY
CLINIC	The following phases are presented: Incubation period: 7 to 10 days Catarrhal phase: clinical manifestations of mild infections of a few days, up to 2 weeks, with the presence of (runny nose, nasal congestion, sneezing) with involvement in the upper airway. ) Paroxysmal phase: This phase is presented from 2 to 8 weeks with the presence of a cough crisis, which can be either fifth or coke fluke of different intensity, depending on the level of crisis. Mild crisis: cough that does not produce hemoptysis or cyanosis. Moderate crisis: when hemoptysis occurs. Crisis severe: when cyanosis occurs. Phase convalecencia: In this phase is presented in week 8 to 12 weeks, which results in a regression of symptoms, where they disappear throughout the week or over the course of the month	Incubation phase: from 7 to 10 days, they are classified into 3 clinical phases. Catarrhal phase: This occurs from 7 to 14 days, the clinical manifestations, is shown as a respiratory infection with the presence of rhinorrhea, sore throat when swallowing and cough, however in some cases they are low fevers. Paroxysmal phase: Its duration is from 2 to 6 weeks, where it refers to fifth-cough crisis (5 episodes of continuous cough), with presence of inspiratory stridor, which can be seen cyanosis, vomiting caused by cough along with refusal to consume foods. Convalescence Phase: In this phase, the cough begins to decrease, there is no crisis, however, it can occur from 2 to 6 weeks, so care must be taken when contracting future viruses.
DIAGNOSIS	Cough lasting longer than 2 weeks, plus one of the following: • Paroxysmal cough. Inspiratory Extruder • Vomiting after coughing fits without other apparent cause.	It is characterized by: a fifth, paroxysmal cough that causes vomiting and cyanosis, with small intervals of apneas.
DIAGNOSTIC METHODS	Hemogram: Obtained with an increase in leukocytes with lymphocytosis that is suggestive of whooping cough. Culture: positive nasopharyngeal for Bordetella pertussis.	Culture: Nasopharyngeal, where Bordetella pertussis is negative, as well as a PCR. .
TREATMENTS	AN ANTIBIOTICS, LIKE ERYTHROMYCIN, AZITHROMYCIN AND CLARITHROMYCIN, SHOULD BE USED AS A TREATMENT TO STOP BACTERIAL GROWTH OR TO ELIMINATE THEM IN ADDITION TO OXYGEN SUPPORT TO IMPROVE GASEOUS EXCHANGE AND IMPROVE YOUR RESPIRATORY FUNCTION	AN ANTIBIOTICS, LIKE ERYTHROMYCIN, AZITHROMYCIN AND CLARITHROMYCIN, SHOULD BE USED AS A TREATMENT TO STOP BACTERIAL GROWTH OR TO ELIMINATE THEM ALSO OXYGEN SUPPORT TO IMPROVE GASEOUS EXCHANGE AND IMPROVE RESPIRATORY FUNCTION
MECHANIC VENTILATION	LA VENTILACION MECANICA EN ESTOS PACIENTES SE INICIA COMO SECUNDARIA A UNA NEUMONIA O A UNA INSUFICIENCIA RESPIRATORIA SECUNDARIA A APNEA	DEBIDO A QUE CAUSA UN POCESO INFLAMATIRIOA NIVEL PULMONAR EL CUAL NOS AUMENTA LA RESITENCIA, ESTOS PACIENTES PUEDEN LLEGAR A REQUERIR DE VENTILACION MECANICA PIRNCIPALMENTE POR PRESION PARA PODE VENCESER ESTAS RESISTENCIA
VENTILATORY PARAMETERS	UNDER 3 YEARS OLD: • PAW = <30 ​​cmH2O • PEEP = 4-6 cmH2O • FR = 30-60 RPM • FIO2 = ACCORDING TO SatO2 • T. INS = R I / E 1: 2 • SENCIBILITY <1 OVER 8 YEARS OLD: • VT = 5-7 ml / kg • PEEP = 5-7 cmH2O • FR = 12-25 • FIO2 = ACCORDING TO SatO2 • T. INS = R I / E 1: 2 • SENCIBILITY = 1.5 - 2 • FLOW = MINIMUM 10% OF VT FROM 3 TO 8 YEARS: • DUAL MODES	UNDER 3 YEARS OLD: • PAW = <30 ​​cmH2O • PEEP = 4-6 cmH2O • FR = 30-60 RPM • FIO2 = ACCORDING TO SatO2 • T. INS = R I / E 1: 2 • SENCIBILITY <1 OVER 8 YEARS OLD: • VT OR RAW = 5-7 ml / kg <30 cmH2O • PEEP = 5-7 cmH2O • FR = 12-25 • FIO2 = ACCORDING TO SatO2 • T. INS = R I / E 1: 2 • SENCIBILITY = 1.5 - 2 • FLOW = THE MOST POSSIBLE BITS (MIN 10% OF VT) FROM 3 TO 8 YEARS: • VT, RAW OR DUAL MODES